Analyses of the gene signatures associated with human BRAF and KRAS-mutant CRC revealed that relative to KRAS-mutant CRC, ZEB1 expression in BRAF-mutant CRC was associated with increased expression of genes related to angiogenesis, and immune and decreased apoptosis signature (Figure 7A and Supplemental Tables 5 and 6). Here, KRAS is linked to colorectal carcinoma.