MDM2 and colorectal carcinoma: Some genes were regulated by ZEB1 specifically in either KRAS or BRAF-mutant CRC cells; for instance, in KRAS-mutant CRC cells, ZEB1 downregulation increased CDC25A expression and reduced that of ADAM17 (involved in catabolic or proteolytic processes), MDM2, CENPF, DICER1, and TICAM2 (involved in cell division).