TP53 and systemic lupus erythematosus: It is noteworthy that anti-p53 IgG signals in patients with SLE were significantly higher than those in healthy subjects [median signal, 0.073 (IQR, 0.067–0.108) vs. 0.26 (IQR, 0.153–0.498); P = 0.011] (Supplementary Fig. S11C).