HGF and colorectal carcinoma: HGF and CXCL8 levels in the supernatant were significantly decreased in circNOLC1‐depleted HCT116 cells only when HCT116 cells were co‐cultured with the normal liver cells, while no changes were observed when co‐cultured with normal lung cells (Figure 2G), suggesting that circNOLC1 was indispensable for CRC liver metastasis.