CXCL2 and infection: Cxcl2 was a chemokine associated with proinflammatory function and its downregulation inhibited the recruitment of polymorphonuclear cells, which were responsible for the elimination of monocytogenes during infection.[32] Gene ontology (GO) analysis of cellular components based on DEGs showed that ECM was different between the HP‐sEVs and control groups, indicating that HP‐sEVs may repair IVD by promoting ECM regeneration (Figure 6d).