ING4 could induce PD‐L1 autophagic degradation resulting in inhibition of NSCLC immune escape, while alignment analysis showed that ING4 contains a consensus CK2 phosphorylation motif (Figure5A), suggesting that CK2 could induce ING4‐S150 phosphorylation, which was demonstrated by LC/MS/MS (Figure 5B). This evidence concerns the gene CD274 and non-small cell lung carcinoma.