EPO has shown neuron protection from apoptosis induced by ethanol and lithium–pilocarpine-induced status epilepticus in different parts of the brain such as the hippocampus, cerebellum, and prefrontal cortex (Kumral et al., 2005; Sözmen et al., 2012; Vittori et al., 2021). The gene discussed is EPO; the disease is status epilepticus.