BMPR2 and pulmonary arterial hypertension: We sought to recapitulate these findings using two rodent models of RV dysfunction: (1) mice with universal expression of BMPR2 mutation associated with heritable forms of PAH (BMPR2R899X), which we have previously shown to develop disproportional RV dysfunction to pulmonary vascular disease (35) and (2) pulmonary artery banding (PAB), a pure RV load-stress model.