IFNA1 and bacterial infectious disease: Moreover, some DEGs are enriched in infectious viral and bacterial diseases (hsa05163, hsa05134, hsa05171, hsa05131, hsa05133, hsa05135, hsa05132, hsa05130, hsa05162, hsa05164, and hsa05167) and in signaling pathways (hsa04620 and hsa04217) that are important in the immune defense against viral, bacterial, fungal pathogens, and parasites (21) and in mediating of inflammation by inducing type 1 interferon (IFN) production (hsa04623) (22).