(24) found that the combination of photothermal therapy (PTT) based on PEG-polylactic acid-hydroxyacetic acid copolymer (PLGA) and iron oxide nanoparticles with anti-PD-1 exhibited substantial CD8+ T cell infiltration, almost complete inhibition of tumor growth, and significantly improved survival in mice compared to the control and anti-PD-1 groups alone. Here, CD8A is linked to neoplasm.