In addition, CD8+ T lymphocyte and natural killer cell activities were significantly increased in the combination treatment group, and the mice with complete tumor regression were able to resist secondary attacks by tumor cells, demonstrating that nanoparticle-based magnetic thermotherapy combined with DC treatment can prolong tumor immunity, creating new possibilities for the use of eosinophilic lymphocytes for clinical applications in solid tumors. This evidence concerns the gene CD8A and neoplasm.