The results showed significantly increased expression of these genes in HCC cells (PLC, SK, LM3, HepG2 and HuH-7) (Figures 5A–G) and tumor tissues from 20 patients diagnosed with hepatocellular carcinoma (Figures 5H–N), consistent with these of the bioinformatics analysis. The gene discussed is HSPG2; the disease is hepatocellular carcinoma.