Biomarkers can help monitor disease progression and treatment responsein cardiovascular diseases by reflecting changes in cardiac function,inflammation, and tissue damage.123 Forinstance, in heart failure, monitoring BNP and NT-proBNP levels overtime can help assess changes in cardiac strain and the effectivenessof medications.124 Troponin levels arecommonly monitored to track myocardial damage in acute coronary syndromeand evaluate the success of interventions like angioplasty.125 These indications can help physicians makethe correct diagnoses and treat patients accordingly. Here, NPPB is linked to heart failure.