Interestingly, significantly increased mRNA levels of BIRC2 (c-IAP1) and BIRC3 (c-IAP2) were observed when PC3 and C4–2B cells were infected with M. hyorhinis (Fig. 6D and E), suggesting that M. hyorhinis infection prevents PCa cells from undergoing high TNF-α-mediated cell death by modulating BIRC2 and BIRC3 expression. This evidence concerns the gene TNF and posterior cortical atrophy.