Furthermore, this percentage of high TNF mRNA expressing Prostate Adenocarcinoma patients (altered group; Log2 Ratio = 3.18; p = 1.67E-18; Fig. S2A) also presented a greater level of lymph node metastasis than the unaltered group (Fig. S2B). This evidence concerns the gene TNF and metastatic malignant neoplasm in the lymph nodes.