Our analysis also showed that a higher degree of TNF-α was associated with greater lymph node metastasis and a higher degree of advanced stages of cancer in prostate adenocarcinoma, uterine corpus endometrial carcinoma, and bladder urothelial carcinoma (Fig. S2 and Fig. S3). The gene discussed is TNF; the disease is metastatic malignant neoplasm in the lymph nodes.