Jia D. et al identified the genes such as IL-13RA2, CCL2, IL-6, TLR2, COL1A2, TIMP1, THBS1, and SERPINE1 in the TME of glioma patients associated with poor prognosis based on the ESTIMATE algorithm (Jia et al., 2018). Here, IL13RA2 is linked to glioma.