Focusing on the histology (Figure 3D), our meta-analysis confirms that DICER1 mutations can frequently occur in follicular-pattern lesions, as PTC follicular subtype (either alone or with the PDTC component), PTC solid subtype, FTC, and Hurtle cell carcinoma (collectively 20%), as well as in benign/premalignant lesions (adenoma, nodular goiter, and follicular adenoma, collectively computed as unique class, 19%), and also in less differentiated TCs (PDTC+ATC 19%). This evidence concerns the gene DICER1 and nodular goiter.