VWCE and diabetes mellitus: Furthermore, by intersecting 2,057 immune score-related module genes and 278 DEGs between DR and DM samples, a total of 15 common genes, namely, CCDC144B, CFAP298-TCP10L, Family with sequence similarity 209 member B (FAM209B), GUSBP17, IGKJ3, KANTR, KRT1, MEF2C-AS2, OCIAD1-AS1, POM121 membrane glycoprotein-like 1 pseudogene (POM121L1P), Prostaglandin E synthetase (PTGES), TRGV5P, VWCE, WNT4, and ZNF876P, were obtained as significantly differential target genes relevant to immune scores (Figure 1G).