POM121L1P and early-onset autosomal dominant Alzheimer disease: For the KEGG enrichment results, the signaling pathways of antigen processing and presentation and viral myocarditis were highly enriched by FAM209B. POM121L1P and PTGES were common to the pathways of Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and oxidative phosphorylation (Figures 5A–C).