USP7 and neoplasm: The nude mice were sacrificed at 3 weeks after injection, tumours were photographed (Fig. 2F, left panel) and their weights were analyzed (Fig. 2F, right panel), showing that the shUSP7 group had smaller tumours while the shUSP7shDICER group almost completely reverse the tumour‐suppressing effect of USP7 knockdown in vivo.