Firstly, the tubular structure formation of vascular mimicry (VM) was greatly weakened in the shUSP7 group, which was almost recovered in the shUSP7shDICER group in both MDA‐MB‐231 and DU145 cells, suggesting that USP7 regulated the ability of vascular mimicry formation of tumour cells at least partially through DICER (Fig. S2A). The gene discussed is USP7; the disease is neoplasm.