NT5E and neoplasm: Overexpression of CD73 did not have an inhibitory effect on KPC or Panc02 cell proliferation in vitro (Figure S2B,C, Supporting Information), but it significantly increased tumor volume and weight compared to the control cells in both subcutaneously implanted murine models in C57BL/6 mice (Figure 2D–F; Figure S2D–F, Supporting Information).