IL18 and infection: Flagellin induces NLRC4 inflammasome‐dependent activation of Caspase‐1 cell divisions, leading to the release of IL‐1β, IL‐18, and eventual pyroptosis in cells and causing tissue injury.[38] Infection with rSC0119(pS‐SaoAACA−) triggered Caspase‐1 processing, enriching the activation of the 20 kDa subunit (Figure 5D).