MYC and neoplasm: In part at least, the tumour suppressive role of FBXW7 has been ascribed to its ability to drive the ubiquitination and degradation of oncoproteins including c‐MYC [11, 12, 13], NOTCH [14, 15, 16], c‐JUN [17, 18], Cyclin E [7, 10, 19] and MCL1 [1], as well as pro‐aneuploidy factors such as Aurora A [20, 21].