GLA and Fabry disease: Fabry disease (FD; Online Mendelian Inheritance in Man® MIM Number: 301500) is a rare, X-linked, lysosomal storage disorder arising from α-galactosidase-A (GLA, MIM: 300644) gene mutations, causing deficiency of the α-galactosidase-A (α-Gal-A) enzyme [1, 2].