To investigate the functional importance of MYBL2 in OVC development, we generated a mouse model of ovarian cancer by injection of syngenetic ID-8 mouse ovarian cancer cells with lentivirus encoding green fluorescent protein (GFP)-tagged control scrambled shRNA (shNC) or MYBL2-targeting shMYBL2 (shMYBL2-1, shMYBL2-3) into the right ovarian bursae of C57BL/6 mice (Supplementary Fig. 1F). Here, MYBL2 is linked to ovarian cancer.