Conversely, co-transfection of Notch1 inhibitors in P-MSCs with CSF2 knockdown showed rescued the inhibitory effect of CSF inhibitors, including augmented tropism towards gastric cancer cells (Fig. 6A), enhanced expression of FAP and α-SMA (Fig. 6B, C), elevated expression of inflammatory factors GM-CSF, FGF, and PDGF-BB (Fig. 6D). The gene discussed is ACTA1; the disease is gastric cancer.