The main pathogenesis mechanisms of neurodegenerative diseases included abnormalities in the intercellular ubiquitin‐proteasome system, changes in cytoskeletal proteins, and continuous deposition of insoluble protein inclusion bodies in the cytoplasm or nucleus, such as β‐amyloid deposition, neurofibrillary degeneration, and Lewy body formation.2 The gene discussed is DNM2; the disease is neurodegenerative disease.