AKT1 and Alzheimer disease: Dynamin‐1 and AP2B1 proteins regulated autophagy activity through PI3K‐I/Akt‐AMPK‐mTOR and PI3K‐I/Akt–mTOR signaling pathways to affect the levels of aging markers (p21, p35/25, and p16) and inflammatory factors (tumor necrosis factor‐α and NF‐κB), which reduced the expression of AD marker proteins tau and Aβ, thereby delaying the pathological process of AD.54