TARDBP and Alzheimer disease: Substantiating its significance as a marker of pathology, TDP-43 has also been identified as a component of cytoplasmic aggregates in dementias other than FTD, including Alzheimer’s disease (AD) [13–15], AD with Lewy body dementia (AD/LBD) [16], Parkinsonism-dementia complex (PDC) [17], and hippocampal sclerosis [18].