To model FTD-like TDP-43 proteinopathy we used a highly specific split GAL4 driver line SS01276 available from the Janelia FlyLight Split-GAL4 Driver Collection [81] to express human TDP-43 [98] in a subset of MBNs that form the α/β and γ lobes of the adult Drosophila MBs. Here, TARDBP is linked to frontotemporal dementia.