The variables that composed the model previously constructed in the SERVE-HF cohort [13], age, treatment group allocation (ASV or control), male sex, SBP < 120 mmHg, diabetes, diuretic, cardiac device and 6 min walk distance and NT‐proBNP, in addition to atrial fibrillation, were considered in the stratification process (Fig. 2A). The gene discussed is NPPB; the disease is hydrops fetalis.