K70 induced death mediated by sepsis, bacterial infection, malignant neoplasm, volume depletion, delirium, cardiac arrest, intracerebral haemorrhage, respiratory failure, chronic kidney disease, diabetes mellitus, osteoporosis, disorders of fluid, electrolyte, and acid–base balance, etc. In addition, the downstream diseases of K76 were nearly identical to those of K70, except for cardiac arrest. The gene discussed is KRT76; the disease is osteoporosis.