GSDMD and dry age related macular degeneration: The few studies investigating the role of GSDMD in the retina have predominantly utilised cell-culture-based techniques and focused only on the RPE using amyloid beta (Aβ) (a toxic component known to accumulate in dry-AMD) treated aRPE-19 cells [31, 32] or Alu RNA (a transposon group implicated in dry-AMD) transfected human RPE cells [7, 33].