MRC1 and atherosclerosis: Notably, CD163+/CD206+ (also known as mannose receptor, Mrc1) macrophages, M(Hb), often involved in autoimmune response, do not always confer protection against atherosclerosis because CD163+ macrophages can promote angiogenesis, vascular permeability and inflammatory cell recruitment via the CD163-HIF1α-VEGFA pathway [98, 99].