Wang KH et al. illustrated that methylated PCDHA13 and PCDHA4 were closely associated with the severity and progression of cervical carcinoma, and PCDHA13 and PCDHA3 were considered screening biomarkers with more specificity and equal sensitivity when combined with HPV to test cervical cancers compared with the HPV test alone [35]. The gene discussed is PCDHA4; the disease is cervical carcinoma.