Although it has not yet been demonstrated experimentally, some authors suggest that DHRS1 may constitute a unique and independent predictive biomarker and a potential therapeutic target for HCC.[9] Prognostic prediction models based on DHRS1-related immune genes have been established, which have proven to be both effective and reliable, suggesting a role for DHRS1 in the infiltration of immune cells in HCC. The gene discussed is DHRS1; the disease is hepatocellular carcinoma.