In BC patients group, the serum levels of FTO (0.464 [0.439, 0.550] ng/mL) and PIK3CB (4.325 [3.310, 5.885] ng/mL) were found to be remarkably increased compared to healthy controls (P < .001; Figure 1A and B, Supplementary Table 2, http://links.lww.com/MD/K38). The gene discussed is PIK3CB; the disease is breast cancer.