CD4 and psoriasis: In line with previous studies,[54,55] correlation analysis demonstrated PDGs was positively linked with proinflammatory infiltration of immune cells (e.g., Macrophages M0 and M1, T cells CD4 memory activated), and negatively linked with anti-inflammatory (e.g., Macrophages M2) or regulatory (e.g., T cells regulatory) immune cell infiltrations, which might due to the psoriasis pathogenesis of high immune infiltration and abnormal proliferation of KC.