PRMT5 expression was moderately to strongly correlated (Pearson score ≥ 0.4) with established DDR genes such as BRCA1, BRCA2, RAD51, RAD51D, RAD51AP1, FANCA, and FANCI across 125 ovarian and breast cancer cell lines (Fig. 1B). The gene discussed is PRMT5; the disease is breast carcinoma.