Our results showed that both of M1 and M2 macrophages increased significantly after AMI, after intraperitoneal of M-CSF, M2 macrophages in the MM Group were significantly more than those in MC Group, and the expression level of M2 macrophages in the MM Group was also higher than that of M1 macrophages. The gene discussed is CSF1; the disease is Miyoshi myopathy.