In some cancer tissues, such as BLCA (OS, HR = 1.68, p = 0.0005), THYM (OS, HR = 4.26, p = 0.02), KIRC (OS, HR = 2.56, p = 0.002), LIHC (OS, HR = 1.64, p = 0.005), SARC (OS, HR = 1.9, p = 0.008), LUAD (OS, HR = 1.43, p = 0.015), OV (OS, HR = 1.38, p = 0.014), PAAD (OS, HR = 2.00, p = 0.003), KIRP (RFS, HR = 3.44, p = 0.001), LIHC (RFS, HR = 1.46, p = 0.025), TGCT (RFS, HR = 3.44, p = 0.032), and PAAD (RFS, HR = 3.21, p = 0.006), high expression of PCSK9 correlated with poor OS and RFS. Here, PCSK9 is linked to cancer.