The Bcl-2 family gene BCL2 Antagonist/Killer 1 (BAK1) was found expressed at high levels in the apoptotic tissues of several clinical diseases (Zhou et al., 2008; Xu et al., 2011; Magee et al., 2014), and EM has been shown by some scholars to be a pathological consequence of inflammation and apoptosis (Laganà et al., 2019); thus, the high expression of BAK1 is involved in the pathomechanical process that regulates inflammation and apoptosis in the endometrium of EM patients. This evidence concerns the gene BCL2 and erythema multiforme.