DLL4 and glioblastoma: Figure 6d shows the disease module associated with Glioblastoma. Deregulation of NOTCH receptors and their ligands (nodes NOTCH1, NOTCH2, NOTCH3, JAG1, JAG 2, DLL1, DLL3, and DLL4) are known to play a role in Glioblastoma (Fiaschetti et al. 2014); but the role of MFNG is not established.