Among these, six have high bridgeness values, thus likely have a global influence over the network: HSPA8 (AD, PD, SCH), ACTB (PD, SCH), TUBB (FTD, SCH), STXBP1(AD, PD, FTD, SCH, ID), NSF (PD), and TUBA1A (SCH). This evidence concerns the gene ACTB and Parkinson disease.