CCL2 and Behcet disease: There is also research that shows a functional variant of miR-196a2 confers risk for BD, but not for Vogt–Koyanagi–Harada (VKH) syndrome or acute anterior uveitis (AAU), by modulating the expression of the miR-196a gene and regulating the production of pro-inflammatory IL-1β and monocyte chemoattractant protein-1 (MCP-1) (24).