Such disease usually leaves most organs in an inflammatory state and tissue damage, and the degree of inflammation of each organ is often used as an important reference indicator for SLE activity scores, including the level of C-reactive protein (CRP), a standard marker of inflammation, decreased erythrocyte sedimentation rate (ESR) possibly triggered by inflammation and anemia (57, 58). The gene discussed is CRP; the disease is systemic lupus erythematosus.