GCG and hydrops fetalis: According to their research, the GLP-1 RA could considerably lower the incidence of HF hospital admission by 11% (HR vs. placebo of 0.89; 95% CI: 0.82-0.98) [33]. All eight CVOTs for GLP-1 RAs, with the exception of semaglutide (HR: 1.11, 95% CI: 0.77-1.61), show HRs of <1.