As demonstrated in Figure 3C, the downregulation of survivin expression by mifepristone in HCC cells was partially or entirely reversed after MG132 treatment (lane 2 vs. lane 4; 0.2 vs. 1.1 [HepG2], 0.3 vs. 0.6 [Huh7]; 0.8 vs. 1.2 [J7]). The gene discussed is BIRC5; the disease is hepatocellular carcinoma.