FMNL1 and cancer: Totally, based on the interactions among cell types, we explained the formation of the inflamed TME of patients with high FMNL1 expression, and further explored the unique and potential targeted ligand-receptor pairs between the T/NK (FMNL1+) / myeloid (FMNL1+) and malignant cells.Furthermore, we also explored the various expression of FMNL1 in different cell types in pan-cancer.