The identified PPVs are associated with the development of coronary heart disease (ACE, THBD, LDLR, etc.), ischemic stroke (F5, GP1BA), Alzheimer's (APOE, CD33, TREM2, SORL1), neonatal conditions(SFTPA1, SFTPA2, SFTPB, SFTPD), lung cancer (SEMA3B, WNT5B, RECK), respiratory infection (ADAM33, CCL1, CXCL1, MUC1), diabetes mellitus (INS, EGFL8, KIR3DL1), diarrheal diseases (LTF, UGT1A7, UGT1A8, UGT1A9, UGT2B7), and kidney disease (ACE, AGT, PXDN, COLEC11). This evidence concerns the gene KIR3DL1 and kidney disorder.