PCSK1 and plasma cell myeloma: To further confirm the specific type of cell death induced by ART, we sequentially treated two myeloma cell lines with ART and a series of specific cell death inhibitors, including ferrostatin-1 (Fer-1, ferroptosis-specific inhibitor), necrostatin-1 (Nec-1, cell necrosis-specific inhibitor) and 3-methyladenine (3-MA, autophagy-specific inhibitor) (Fig. 2A, B-Right).