Importantly, DHA prevents and reverses fibrosis in a NASH mouse model (Depner et al, 2013a; Lytle et al, 2015) and decreases expression of two out of three collagen encoding genes (COL1A1, COL1A2, COL4A1) that are upregulated in liver cancer and NASH (Appendix Fig S1D). Here, COL1A2 is linked to liver cancer.