BTC and metabolic dysfunction-associated steatohepatitis: We next confirmed that Btc gene expression was increased in other models of NASH, liver cancer and fibrosis including a chemically induced disease (Green et al, 2022; Hammad et al, 2023; Fig EV4B), and it was downregulated by both EPA and DHA in our prevention model, albeit DHA had a stronger effect than EPA (Fig 3D, left panel).