Among different cell types, most of the ω3 PUFA‐regulated genes were assigned to one of the two major hepatic macrophage subpopulations including NASH‐associated macrophages (NAM, 1,455 genes) and Kupffer‐like cells (KC, 585 genes), named according to the previous study (Xiong et al, 2019). This evidence concerns the gene STAC3 and metabolic dysfunction-associated steatohepatitis.