GHRL and congestive heart failure: As ghrelin and the fact that ghrelin and its analogues have already been used in several clinical trials as a therapeutic strategy for the treatment of conditions such as cachexia in chronic heart failure, frailty in the elderly, anorexia nervosa, growth hormone deficient patients (Akamizu & Kangawa, 2012; Strasser, 2012), the findings of this study provide ghrelin as an effective intervention to delay premature aging in HGPS and normal cellular aging, thus enhancing healthspan and lifespan.