To unravel the molecular mechanism by which activin B plays a role in the activation of normal fibroblasts of GC, we performed transcriptome analysis (RNA-Seq) on fibroblasts stimulated by exogenous recombinant human activin B or co-cultured with GC cells (HGC-27 shNC/HGC-27 shINHBB, MGC-803 shNC/MGC-803 shINHBB, MKN-45 Vector/MKN-45 INHBB). Here, INHBB is linked to gastric cancer.