The mean difference in nadir Hb concentrations between SLDPQ treated G6PDd and G6PD normal malaria patients is ~ 1 g/dL [27, 28, 31], but at the higher primaquine doses used by Shekalaghe et al., 0.75 − 1.0 mg/kg, the mean difference was 2 g/dL between the G6PDd and G6PD normal children [34]. Here, GSTM1 is linked to malaria.