ABCB1 and short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome: However, our analysis showed that the frequency of variant homozygous (TTT/TTT) of all three ABCB1 SNPs was significantly higher (5.6 times higher) in the AAMS group than in the N-AAMS group, and that carriers of the TTT/TTT diplotype could be associated with a higher risk of SAMS, OR 7.222 (1.772–26.80, 95% CI, p = 0.0081).